Reproduction, Pregnancy and Programming Journal Club Wednesdays (every other week) 9AM- 11AM Location: MSB M3-37Email Dr. Helen Jones, Dr. Rebecca Wilson or Dr. Brad Daigneault for more information DATE SPEAKER TOPIC January 15, 2025 Dr Rebecca Wilson Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth February 5, 2025 Baylea Davenport Regulation of macrophage polarization by metformin through inhibition of TLR4/NF-κB pathway to improve pre-eclampsia February 12, 2025 Aditya Mahadevan The relationship between abnormal fetoplacental Dopplers, angiogenic markers of placental dysfunction and adverse perinatal outcomes in diabetic pregnancies with small fetuses – A prospective study February 26, 2025 Alyssa Tipler FMS-like tyrosine kinase 1 (FLT1) is a key regulator of fetoplacental endothelial cell migration and angiogenesis March 12, 2025 Haley Wilt Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice March 26, 2025 Brad Daigneault, Ph.D Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals April 9, 2025 Group paper discussion Protective effects of human breast milk-derived exosomes on inflammatory bowel disease through modulation of immune cells April 23 2025 Group paper discussion Exposure to unmethylated CpG oligonucleotides disrupts blood pressure circadian rhythms and placental clock gene network in pregnant rats