Cardio/Renal Journal Club Mondays, 3:00pm-4:00pmLocation: MSB, M559Email Dr. Michelle Gumz or Dr. Ryan Crislip for more information DATE SPEAKER TOPIC January 13, 2025 N/A Organizational Meeting January 27, 2025 Faisal Alousi β2-Adrenergic receptor agonists as a treatment for diabetic kidney disease February 3, 2025 Speed Journal Club Each student will quickly summarize a different cardio-renal-related article of their choosing February 10, 2025 Sophia Elkenberry Prenatal Dexamethasone Programs Autonomic Dysregulation in Female Rats February 24, 2025 Niharika Bala Deletion of AT1a receptors selectively in the proximal tubules of the kidney alters the hypotensive and natriuretic response to atrial natriuretic peptide via NPRA/cGMP/NO signaling March 3, 2025 Group paper discussion Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists March 10, 2025 Group paper discussion (part 2) Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists March 24, 2025 Jacob Ricci CD4+TEM cells drive the progression from acute myocarditis to dilated cardiomyopathy in CVB3-induced BALB/c mice March 31, 2025 Group paper discussion Involvement of Mineralocorticoid Receptor Activation by High Mobility Group Box 1 and Receptor for Advanced Glycation End Products in the Development of Acute Kidney Injury April 7, 2025 Alex Juffre Counteracting Angiotensinogen Small-Interfering RNA-Mediated Antihypertensive Effects With REVERSIR April 21, 2025 Speed Journal Club Faisal Alousi – Extracellular Vesicles From Preeclampsia Disrupt the Blood-Brain Barrier by Reducing CLDN5 Alexandria Juffre – ASK1 limits kidney glucose reabsorption, growth, and mid-late proximal tubule KIM-1 induction when diabetes and Western diet are combined with SGLT2 inhibition Jacob Ricci – Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting Niharika Bala – The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury Sophia Eikenberry – ACE Inhibition to Distinguish Low-Renin Hypertension From Primary Aldosteronism