Rebecca L Wilson

Rebecca L Wilson,

RES AST PROF

Department: Department of Physiology and Aging
Business Phone: (352) 846-0586
Business Email: rebecca.wilson@ufl.edu

Teaching Profile

Courses Taught
2023
GMS6491 Journal Club in Physiology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-3867-7784

Areas of Interest
  • Developmental Origins of Health and Disease
  • Fetal Development
  • Maternal and Child Health
  • Medical complications of pregnancy
  • Placenta
  • Pregnancy Therapies

Publications

2023
HAND1 knockdown disrupts trophoblast global gene expression
Physiological Reports. 11(2) [DOI] 10.14814/phy2.15553. [PMID] 36695714.
2023
Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.06.16.545278. [PMID] 38168281.
2023
Placental nanoparticle gene therapy normalizes gene expression changes in the fetal liver associated with fetal growth restriction in a fetal sex-specific manner
Journal of Developmental Origins of Health and Disease. 14(3):325-332 [DOI] 10.1017/s2040174423000016.
2023
Placental nanoparticle gene therapy normalizes gene expression changes in the fetal liver associated with fetal growth restriction in a fetal sex-specific manner
Developmental Origins of Health and Disease. [DOI] Forthcoming.
2022
Analysis of commonly expressed genes between first trimester fetal heart and placenta cell types in the context of congenital heart disease.
Scientific reports. 12(1) [DOI] 10.1038/s41598-022-14955-8. [PMID] 35750800.
2022
Interventions for placental insufficiency and fetal growth restriction.
Placenta. 125:4-9 [DOI] 10.1016/j.placenta.2022.03.127. [PMID] 35414477.
2022
Nanoparticle‐mediated transgene expression of insulin‐like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations
Molecular Reproduction and Development. 89(11):540-553 [DOI] 10.1002/mrd.23644. [PMID] 36094907.
2022
Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome
Placenta. 117:131-138 [DOI] 10.1016/j.placenta.2021.12.001.
2022
Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in guinea pig sub-placenta/decidua.
Frontiers in physiology. 13 [DOI] 10.3389/fphys.2022.1055234. [PMID] 36685211.
2021
A sexually dimorphic murine model of IUGR induced by embryo transfer.
Reproduction (Cambridge, England). 161(2):135-144 [DOI] 10.1530/REP-20-0209. [PMID] 33434162.
2021
Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy.
International journal of molecular sciences. 22(17) [DOI] 10.3390/ijms22179532. [PMID] 34502440.
2021
Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 320(5):R653-R662 [DOI] 10.1152/ajpregu.00250.2020. [PMID] 33621475.
2021
Sexual dimorphisms in brain gene expression in the growth-restricted guinea pig can be modulated with intra-placental therapy
Pediatric Research. 89(7):1673-1680 [DOI] 10.1038/s41390-021-01362-4. [PMID] 33531677.
2021
Targeting the Dysfunctional Placenta to Improve Pregnancy Outcomes Based on Lessons Learned in Cancer
Clinical Therapeutics. 43(2):246-264 [DOI] 10.1016/j.clinthera.2020.12.007.
2021
Time Mating Guinea Pigs by Monitoring Changes to the Vaginal Membrane throughout the Estrus Cycle and with Ultrasound Confirmation.
Methods and protocols. 4(3) [DOI] 10.3390/mps4030058. [PMID] 34564304.
2020
Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function.
Placenta. 93:1-7 [DOI] 10.1016/j.placenta.2020.02.006. [PMID] 32090963.
2020
Pregnancy, but not dietary octanoic acid supplementation, stimulates the ghrelin-pituitary growth hormone axis in mice.
The Journal of endocrinology. 245(2):327-342 [DOI] 10.1530/JOE-20-0072. [PMID] 32176867.
2020
Reduced Dietary Calcium and Vitamin D Results in Preterm Birth and Altered Placental Morphogenesis in Mice During Pregnancy.
Reproductive sciences (Thousand Oaks, Calif.). 27(6):1330-1339 [DOI] 10.1007/s43032-019-00116-2. [PMID] 32046423.
2019
Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation
Epigenetics. 14(7):660-671 [DOI] 10.1080/15592294.2019.1609866. [PMID] 31038385.
2019
Maternal Selenium, Copper and Zinc Concentrations in Early Pregnancy, and the Association with Fertility
Nutrients. 11(7) [DOI] 10.3390/nu11071609. [PMID] 31315178.
2019
Validation studies of a fluorescent method to measure placental glucose transport in mice.
Placenta. 76:23-29 [DOI] 10.1016/j.placenta.2019.01.014. [PMID] 30803711.
2018
Early pregnancy maternal trace mineral status and the association with adverse pregnancy outcome in a cohort of Australian women.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 46:103-109 [DOI] 10.1016/j.jtemb.2017.11.016. [PMID] 29413099.
2018
Isolation of villous cytotrophoblasts from second trimester human placentas.
Placenta. 74:55-58 [DOI] 10.1016/j.placenta.2018.11.007. [PMID] 30541665.
2018
Pre-pregnancy fast food and fruit intake is associated with time to pregnancy.
Human reproduction (Oxford, England). 33(6):1063-1070 [DOI] 10.1093/humrep/dey079. [PMID] 29733398.
2018
Vitamin D levels in an Australian and New Zealand cohort and the association with pregnancy outcome.
BMC pregnancy and childbirth. 18(1) [DOI] 10.1186/s12884-018-1887-x. [PMID] 29925344.
2017
Zinc is a critical regulator of placental morphogenesis and maternal hemodynamics during pregnancy in mice.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-15085-2. [PMID] 29123159.
2016
Association between Maternal Zinc Status, Dietary Zinc Intake and Pregnancy Complications: A Systematic Review.
Nutrients. 8(10) [PMID] 27754451.
2015
The effect of Vdr gene ablation on global gene expression in the mouse placenta.
Genomics data. 6:72-3 [DOI] 10.1016/j.gdata.2015.08.022. [PMID] 26697339.
2015
Vitamin D Receptor Gene Ablation in the Conceptus Has Limited Effects on Placental Morphology, Function and Pregnancy Outcome.
PloS one. 10(6) [DOI] 10.1371/journal.pone.0131287. [PMID] 26121239.

Grants

Aug 2023 ACTIVE
Efficacy and safety of nanoparticle mediated placental gene therapy in nonhuman primates
Role: Co-Investigator
Funding: NATL INST OF HLTH NICHD
Jul 2023 ACTIVE
Developmental Programming of the Liver and Kidney in Fetal Growth with or without Gene Therapy
Role: Principal Investigator
Funding: NATL INST OF HLTH NICHD

Contact Details

Phones:
Business:
(352) 846-0586
Emails:
Addresses:
Business Mailing:
PO Box 100274
Physiology and Aging
GAINESVILLE FL 32611