Marco Pahor, M.D.
Professor & Director, Institute On Aging
Department:
Department of Physiology and Aging
Business Phone:
(352) 294-5800
Business Email:
mpahor@ufl.edu
About Marco Pahor
MARCO PAHOR, M.D., is the director of the University of Florida Institute on Aging .
Pahor is an internationally recognized expert on population-based studies, clinical trials and multidisciplinary translational research in the fields of aging, disability and cardiovascular disease.
An experienced geriatrician and epidemiologist, Pahor has an excellent publication record, having authored or co-authored more than 450 papers in leading peer-reviewed journals, which have been cited by other researchers more than 5,0000 times. He has an extensive portfolio of grants from the National Institutes of Health and other agencies, and is a leader in research and education, serving as director of the Claude D. Pepper Older Americans Independence Center and of the faculty mentoring program of the UF Clinical and Translational Science Institute.
Before coming to UF in 2005, Pahor held a number of positions at Wake Forest University, including director of the Sticht Center on Aging, deputy associate dean of the office of research and head of the section on gerontology and geriatrics. His previous academic appointments were at the University of Tennessee, the National Institutes of Health, the University of Florence, Italy, and the Catholic University in Rome, where he also earned his medical degree and completed residency.
Pahor is on the Physical Exercise Task Force and the Aging Clinical Trials Advisory Panel of the National Institute on Aging. He has served as an editor for a number of academic journals, including Aging, Clinical and Experimental Research, the Journal of the American Geriatrics Society, the Journal of Gerontology: Medical Sciences and the Journal of Nutrition, Health and Aging. He has served on numerous NIH grant and program review panels.
Publications
2024
Biomarkers of Cellular Senescence Predict the Onset of Mobility Disability and Are Reduced by Physical Activity in Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences.
79(3)
[DOI] 10.1093/gerona/glad257.
[PMID] 37948612.
2024
Use of Minimally Invasive Methods to Assess Fuel Utilization and Circadian Rhythms in Older Adults.
Journal of visualized experiments : JoVE.
(203)
[DOI] 10.3791/64628.
[PMID] 38251713.
2023
Avoidance-Endurance Model in Older Black Men with Low Back Pain: Exploring Relationships.
Journal of racial and ethnic health disparities.
10(3):1310-1318
[DOI] 10.1007/s40615-022-01316-4.
[PMID] 35501598.
2023
Effect of change of interleukin-6 over time on gait speed response: Results from the lifestyle interventions and independence for elders study.
Mechanisms of ageing and development.
210
[DOI] 10.1016/j.mad.2022.111763.
[PMID] 36526102.
2023
Effect of Physical Activity Intervention on Gait Speed by Frailty Condition: A Randomized Clinical Trial.
Journal of the American Medical Directors Association.
24(4):489-496
[DOI] 10.1016/j.jamda.2023.01.023.
[PMID] 36878264.
2023
Exercise and Behavior: Adjuncts to Pro-Myogenic Compounds for Enhancing Mobility in Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences.
78(Suppl 1):61-66
[DOI] 10.1093/gerona/glad041.
[PMID] 37325956.
2023
Outcome measures for Alzheimer’s disease: A global inter-societal Delphi consensus.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
19(6):2707-2729
[DOI] 10.1002/alz.12945.
[PMID] 36749854.
2023
Supporting physical activity for mobility in older adults with mobility limitations (SuPA Mobility): study protocol for a randomized controlled trial.
Trials.
24(1)
[DOI] 10.1186/s13063-023-07798-9.
[PMID] 38017467.
2022
Analysis of Biological Aging and Risks of All-Cause and Cardiovascular Disease-Specific Death in Cancer Survivors.
JAMA network open.
5(6)
[DOI] 10.1001/jamanetworkopen.2022.18183.
[PMID] 35731518.
2022
Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study.
GeroScience.
44(6):2757-2770
[DOI] 10.1007/s11357-022-00685-2.
[PMID] 36367600.
2022
Cancer and aging: A call to action.
Aging and cancer.
3(2):87-94
[DOI] 10.1002/aac2.12055.
[PMID] 36188489.
2022
Frailty and risk of mortality in older cancer survivors and adults without a cancer history: Evidence from the National Health and Nutrition Examination Survey, 1999-2014.
Cancer.
128(15):2978-2987
[DOI] 10.1002/cncr.34258.
[PMID] 35608563.
2022
Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project).
BMJ (Clinical research ed.).
377
[DOI] 10.1136/bmj-2021-068788.
[PMID] 35545258.
2022
Unexplained anemia of aging: Etiology, health consequences, and diagnostic criteria.
Journal of the American Geriatrics Society.
70(3):891-899
[DOI] 10.1111/jgs.17565.
[PMID] 34796957.
2021
Agreement of Minimum Data Set 3.0 depression and behavioral symptoms with clinical diagnosis in a nursing home.
Aging & mental health.
25(10):1897-1902
[DOI] 10.1080/13607863.2020.1758921.
[PMID] 32447973.
2021
Clinically Important Differences for Mobility Measures Derived from the Testosterone Trials.
Journal of the American Geriatrics Society.
69(2):517-523
[DOI] 10.1111/jgs.16942.
[PMID] 33210287.
2021
Elevated IL-6 and CRP Levels Are Associated With Incident Self-Reported Major Mobility Disability: A Pooled Analysis of Older Adults With Slow Gait Speed.
The journals of gerontology. Series A, Biological sciences and medical sciences.
76(12):2293-2299
[DOI] 10.1093/gerona/glab093.
[PMID] 33822946.
2021
International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines.
The journal of nutrition, health & aging.
25(7):824-853
[DOI] 10.1007/s12603-021-1665-8.
[PMID] 34409961.
2021
Machine Learning in Aging: An Example of Developing Prediction Models for Serious Fall Injury in Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences.
76(4):647-654
[DOI] 10.1093/gerona/glaa138.
[PMID] 32498077.
2021
Quality of opioid prescribing in older adults with or without Alzheimer disease and related dementia.
Alzheimer's research & therapy.
13(1)
[DOI] 10.1186/s13195-021-00818-3.
[PMID] 33883028.
2021
Ratings of Perceived Exertion During Walking: Predicting Major Mobility Disability and Effect of Structured Physical Activity in Mobility-Limited Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences.
76(10):e264-e271
[DOI] 10.1093/gerona/glab036.
[PMID] 33585918.
2021
Three-Year, Postintervention, Follow-up Comparison of Health Care Resource Utilization and Costs in the Lifestyle Interventions and Independence for Elders (LIFE) Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
76(2):272-276
[DOI] 10.1093/gerona/glaa088.
[PMID] 32270182.
2021
Uncontrolled Pain and Risk for Depression and Behavioral Symptoms in Residents With Dementia.
Journal of the American Medical Directors Association.
22(10):2079-2086.e5
[DOI] 10.1016/j.jamda.2021.05.010.
[PMID] 34089652.
2020
Application of Cut-Points for Low Muscle Strength and Lean Mass in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society.
68(7):1445-1453
[DOI] 10.1111/jgs.16525.
[PMID] 32633836.
2020
Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study.
Journal of clinical medicine.
9(11)
[DOI] 10.3390/jcm9113757.
[PMID] 33266358.
2020
Association of Fish Oil and Physical Activity on Mobility Disability in Older Adults.
Medicine and science in sports and exercise.
52(4):859-867
[DOI] 10.1249/MSS.0000000000002195.
[PMID] 31688650.
2020
Comparative Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Response to a Physical Activity Intervention in Older Adults: Results From the Lifestyle Interventions and Independence for Elders Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
75(5):1010-1016
[DOI] 10.1093/gerona/glz120.
[PMID] 31070702.
2020
Corrigendum: Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience.
12
[DOI] 10.3389/fnagi.2020.00063.
[PMID] 32194394.
2020
Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes: Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference.
The journals of gerontology. Series A, Biological sciences and medical sciences.
75(7):1317-1323
[DOI] 10.1093/gerona/glz081.
[PMID] 30869772.
2020
Healthcare Utilization and Physical Functioning in Older Adults in the United States.
Journal of the American Geriatrics Society.
68(2):266-271
[DOI] 10.1111/jgs.16260.
[PMID] 31755551.
2020
ICFSR Task Force Perspective on Biomarkers for Sarcopenia and Frailty.
The Journal of frailty & aging.
9(1):4-8
[DOI] 10.14283/jfa.2019.32.
[PMID] 32150207.
2020
Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability.
Journal of the American Geriatrics Society.
68(4):872-881
[DOI] 10.1111/jgs.16365.
[PMID] 32105353.
2020
Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study.
Journal of clinical medicine.
9(9)
[DOI] 10.3390/jcm9092989.
[PMID] 32947839.
2020
Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability.
Journal of the American Geriatrics Society.
68(3):619-624
[DOI] 10.1111/jgs.16274.
[PMID] 31867713.
2020
Improving natural product research translation: From source to clinical trial.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
34(1):41-65
[DOI] 10.1096/fj.201902143R.
[PMID] 31914647.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology.
142
[DOI] 10.1016/j.exger.2020.111123.
[PMID] 33191210.
2020
Relationships Between Profiles of Physical Activity and Major Mobility Disability in the LIFE Study.
Journal of the American Geriatrics Society.
68(7):1476-1483
[DOI] 10.1111/jgs.16386.
[PMID] 32196636.
2020
The relationship between interleukin-6 levels and physical performance in mobility-limited older adults with chronic low-grade inflammation: The ENRGISE Pilot study.
Archives of gerontology and geriatrics.
90
[DOI] 10.1016/j.archger.2020.104131.
[PMID] 32554219.
2020
Trajectories of Short Physical Performance Battery Are Strongly Associated with Future Major Mobility Disability: Results from the LIFE Study.
Journal of clinical medicine.
9(8)
[DOI] 10.3390/jcm9082332.
[PMID] 32707877.
2019
A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences.
74(11):1821-1827
[DOI] 10.1093/gerona/glz050.
[PMID] 30778518.
2019
Effect of Gastric Acid Suppressants on Response to a Physical Activity Intervention and Major Mobility Disability in Older Adults: Results from the Lifestyle Interventions for Elders (LIFE) Study.
Pharmacotherapy.
39(8):816-826
[DOI] 10.1002/phar.2299.
[PMID] 31230397.
2019
Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society.
67(2):261-268
[DOI] 10.1111/jgs.15631.
[PMID] 30452084.
2019
Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences.
74(10):1612-1619
[DOI] 10.1093/gerona/gly277.
[PMID] 30541065.
2019
Falls in Older Adults: Prevention, Mortality, and Costs.
JAMA.
321(21):2080-2081
[DOI] 10.1001/jama.2019.6569.
[PMID] 31162553.
2019
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research.
AIDS research and human retroviruses.
35(11-12):999-1012
[DOI] 10.1089/AID.2019.0130.
[PMID] 31456412.
2019
Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience.
11
[DOI] 10.3389/fnagi.2019.00358.
[PMID] 31969814.
2019
Pain Assessments in MDS 3.0: Agreement with Vital Sign Pain Records of Nursing Home Residents.
Journal of the American Geriatrics Society.
67(11):2421-2422
[DOI] 10.1111/jgs.16122.
[PMID] 31403708.
2019
Physical Activity and Performance Impact Long-term Quality of Life in Older Adults at Risk for Major Mobility Disability.
American journal of preventive medicine.
56(1):141-146
[DOI] 10.1016/j.amepre.2018.09.006.
[PMID] 30573142.
2019
Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management.
The journal of nutrition, health & aging.
23(9):771-787
[DOI] 10.1007/s12603-019-1273-z.
[PMID] 31641726.
2019
Prostate-Specific Antigen Levels During Testosterone Treatment of Hypogonadal Older Men: Data from a Controlled Trial.
The Journal of clinical endocrinology and metabolism.
104(12):6238-6246
[DOI] 10.1210/jc.2019-00806.
[PMID] 31504596.
2019
The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study.
Nutrients.
11(7)
[DOI] 10.3390/nu11071500.
[PMID] 31262054.
2019
The Enabling Reduction of Low-Grade Inflammation in Seniors (ENRGISE) Pilot Study: Screening Methods and Recruitment Results.
The journals of gerontology. Series A, Biological sciences and medical sciences.
74(8):1296-1302
[DOI] 10.1093/gerona/gly204.
[PMID] 30202946.
2018
A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
73(4):513-518
[DOI] 10.1093/gerona/glx153.
[PMID] 28958023.
2018
Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults.
Frontiers in aging neuroscience.
10
[DOI] 10.3389/fnagi.2018.00341.
[PMID] 30498440.
2018
Designing Drug Trials for Frailty: ICFSR Task Force 2018.
The Journal of frailty & aging.
7(3):150-154
[DOI] 10.14283/jfa.2018.20.
[PMID] 30095144.
2018
Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
Journal of the American Geriatrics Society.
66(6):1172-1179
[DOI] 10.1111/jgs.15369.
[PMID] 29637543.
2018
Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial.
BMC medicine.
16(1)
[DOI] 10.1186/s12916-018-1174-8.
[PMID] 30352583.
2018
Effect of Physical Activity on Frailty.
Annals of internal medicine.
169(4)
[DOI] 10.7326/L18-0243.
[PMID] 30128516.
2018
Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial.
Annals of internal medicine.
168(5):309-316
[DOI] 10.7326/M16-2011.
[PMID] 29310138.
2018
Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials.
The lancet. Diabetes & endocrinology.
6(11):879-890
[DOI] 10.1016/S2213-8587(18)30171-2.
[PMID] 30366567.
2018
Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis.
Ageing research reviews.
46:42-59
[DOI] 10.1016/j.arr.2018.05.004.
[PMID] 29803716.
2018
Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations.
Journal of the American Geriatrics Society.
66(5):954-961
[DOI] 10.1111/jgs.15331.
[PMID] 29608795.
2018
Implications of ICD-10 for Sarcopenia Clinical Practice and Clinical Trials: Report by the International Conference on Frailty and Sarcopenia Research Task Force.
The Journal of frailty & aging.
7(1):2-9
[DOI] 10.14283/jfa.2017.30.
[PMID] 29412436.
2018
International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management.
The journal of nutrition, health & aging.
22(10):1148-1161
[DOI] 10.1007/s12603-018-1139-9.
[PMID] 30498820.
2018
Lessons From the Testosterone Trials.
Endocrine reviews.
39(3):369-386
[DOI] 10.1210/er.2017-00234.
[PMID] 29522088.
2018
Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
73(5):688-694
[DOI] 10.1093/gerona/glx231.
[PMID] 29490012.
2018
Meta-analysis identifies mitochondrial DNA sequence variants associated with walking speed.
GeroScience.
40(5-6):497-511
[DOI] 10.1007/s11357-018-0043-x.
[PMID] 30338417.
2018
Serious adverse events of older adults in nursing home and community intervention trials.
Contemporary clinical trials communications.
9:77-80
[DOI] 10.1016/j.conctc.2017.12.004.
[PMID] 29696228.
2018
Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study.
The journals of gerontology. Series B, Psychological sciences and social sciences.
73(8):1501-1513
[DOI] 10.1093/geronb/gbx051.
[PMID] 28482106.
2018
The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: Case finding, screening and characteristics of eligible participants.
Experimental gerontology.
113:48-57
[DOI] 10.1016/j.exger.2018.09.017.
[PMID] 30261246.
2018
The Effect of Testosterone on Cardiovascular Biomarkers in the Testosterone Trials.
The Journal of clinical endocrinology and metabolism.
103(2):681-688
[DOI] 10.1210/jc.2017-02243.
[PMID] 29253154.
2018
The exerkine apelin reverses age-associated sarcopenia.
Nature medicine.
24(9):1360-1371
[DOI] 10.1038/s41591-018-0131-6.
[PMID] 30061698.
2018
The Relationship of Omega 3 Polyunsaturated Fatty Acids in Red Blood Cell Membranes with Cognitive Function and Brain Structure: A Review Focussed on Alzheimer’s Disease.
The journal of prevention of Alzheimer's disease.
5(1):78-84
[DOI] 10.14283/jpad.2017.19.
[PMID] 29405237.
2017
A New Adaptive Home-based Exercise Technology among Older Adults Living in Nursing Home: A Pilot Study on Feasibility, Acceptability and Physical Performance.
The journal of nutrition, health & aging.
21(7):819-824
[DOI] 10.1007/s12603-016-0820-0.
[PMID] 28717812.
2017
Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.
Journal of the American Heart Association.
6(12)
[DOI] 10.1161/JAHA.117.007215.
[PMID] 29197830.
2017
Association of Testosterone Levels With Anemia in Older Men: A Controlled Clinical Trial.
JAMA internal medicine.
177(4):480-490
[DOI] 10.1001/jamainternmed.2016.9540.
[PMID] 28241237.
2017
Device-Measured Physical Activity As a Predictor of Disability in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society.
65(10):2251-2256
[DOI] 10.1111/jgs.15037.
[PMID] 28799216.
2017
Dose of physical activity, physical functioning and disability risk in mobility-limited older adults: Results from the LIFE study randomized trial.
PloS one.
12(8)
[DOI] 10.1371/journal.pone.0182155.
[PMID] 28820909.
2017
Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study.
Journal of the American Medical Directors Association.
18(4):312-319
[DOI] 10.1016/j.jamda.2016.10.001.
[PMID] 27914851.
2017
Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study.
Journal of the American Geriatrics Society.
65(5):980-988
[DOI] 10.1111/jgs.14742.
[PMID] 28168689.
2017
Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility.
Journal of the American Geriatrics Society.
65(7):1427-1433
[DOI] 10.1111/jgs.14804.
[PMID] 28221668.
2017
Effects of a Long-Term Physical Activity Program on Activity Patterns in Older Adults.
Medicine and science in sports and exercise.
49(11):2167-2175
[DOI] 10.1249/MSS.0000000000001340.
[PMID] 29045323.
2017
Effects of Physical Activity Intervention on Physical and Cognitive Function in Sedentary Adults With and Without Diabetes.
The journals of gerontology. Series A, Biological sciences and medical sciences.
72(6):861-866
[DOI] 10.1093/gerona/glw179.
[PMID] 27590629.
2017
ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design.
Journal of the American Geriatrics Society.
65(9):1961-1968
[DOI] 10.1111/jgs.14965.
[PMID] 28734043.
2017
Exercise’s effect on mobility disability in older adults with and without obesity: The LIFE study randomized clinical trial.
Obesity (Silver Spring, Md.).
25(7):1199-1205
[DOI] 10.1002/oby.21860.
[PMID] 28653499.
2017
Hippocampal Response to a 24-Month Physical Activity Intervention in Sedentary Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.
25(3):209-217
[DOI] 10.1016/j.jagp.2016.11.007.
[PMID] 27986412.
2017
Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers.
Journal of geriatric oncology.
8(1):69-75
[DOI] 10.1016/j.jgo.2016.09.004.
[PMID] 27743848.
2017
Imputation of Gait Speed for Noncompleters in the 400-Meter Walk: Application to the Lifestyle Interventions for Elders Study.
Journal of the American Geriatrics Society.
65(12):2566-2571
[DOI] 10.1111/jgs.15078.
[PMID] 28884789.
2017
Physical activity and exercise as countermeasures to physical frailty and sarcopenia.
Aging clinical and experimental research.
29(1):35-42
[DOI] 10.1007/s40520-016-0705-4.
[PMID] 28181204.
2017
Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study.
Archives of physical medicine and rehabilitation.
98(1):11-24.e3
[DOI] 10.1016/j.apmr.2016.07.019.
[PMID] 27568165.
2017
Preserving older adults’ routine outdoor activities in contrasting neighborhood environments through a physical activity intervention.
Preventive medicine.
96:87-93
[DOI] 10.1016/j.ypmed.2016.12.049.
[PMID] 28039068.
2017
Prognostic Value of Braden Activity Subscale for Mobility Status in Hospitalized Older Adults.
Journal of hospital medicine.
12(6):396-401
[DOI] 10.12788/jhm.2748.
[PMID] 28574527.
2017
Rationale for a preliminary operational definition of physical frailty and sarcopenia in the SPRINTT trial.
Aging clinical and experimental research.
29(1):81-88
[DOI] 10.1007/s40520-016-0716-1.
[PMID] 28188558.
2017
Resveratrol and exercise to treat functional limitations in late life: design of a randomized controlled trial.
Contemporary clinical trials communications.
6:58-63
[DOI] 10.1016/j.conctc.2017.03.002.
[PMID] 28944303.
2017
Sarcopenia: an overview.
Aging clinical and experimental research.
29(1):11-17
[DOI] 10.1007/s40520-016-0704-5.
[PMID] 28155183.
2017
Systemic inflammation, body composition, and physical performance in old community-dwellers.
Journal of cachexia, sarcopenia and muscle.
8(1):69-77
[DOI] 10.1002/jcsm.12134.
[PMID] 27897412.
2017
Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment.
JAMA.
317(7):717-727
[DOI] 10.1001/jama.2016.21044.
[PMID] 28241356.
2017
The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: design and methods.
Aging clinical and experimental research.
29(1):89-100
[DOI] 10.1007/s40520-016-0715-2.
[PMID] 28144914.
2017
The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial.
BMC medicine.
15(1)
[DOI] 10.1186/s12916-017-0824-6.
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Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study).
Clinical nutrition (Edinburgh, Scotland).
29(4):441-7
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Midarm muscle circumference, physical performance and mortality: Results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study).
American Journal of Clinical Nutrition.
29:441-447
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Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.
Ageing research reviews.
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Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging.
TheScientificWorldJournal.
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2010
Myeloperoxidase levels and mortality in frail community-living elderly individuals.
The journals of gerontology. Series A, Biological sciences and medical sciences.
65(4):369-76
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2010
Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions.
Cardiovascular therapeutics.
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2010
Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment.
The journals of gerontology. Series A, Biological sciences and medical sciences.
65(6):639-47
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2009
A cost analysis of a physical activity intervention for older adults.
Journal of physical activity & health.
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2009
Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study.
Journal of the American Geriatrics Society.
57(2):251-9
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2009
Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.
American heart journal.
157(2):334.e1-8
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2009
Association between inflammatory components and physical function in the health, aging, and body composition study: a principal component analysis approach.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(5):581-9
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2009
C-reactive protein and lipid parameters in older persons aged 80 years and older.
The journal of nutrition, health & aging.
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Carla Task Force On Sarcopenia: Propositions for Clinical Trials
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Carla Task Force on Sarcopenia: propositions for clinical trials.
The journal of nutrition, health & aging.
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2009
Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
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2009
Chronic inflammation is associated with low physical function in older adults across multiple comorbidities.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(4):455-61
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2009
Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study.
Journal of pain and symptom management.
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2009
Effects of Lifestyle Modification On Muscle Strength and Quality in Obese Older Adults
Gerontologist.
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Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(11):1183-9
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2009
Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(4):487-91
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2009
Inflammation and race and gender differences in computerized tomography-measured adipose depots.
Obesity (Silver Spring, Md.).
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2009
Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(1):96-102
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2009
Moderate alcohol intake and risk of functional decline: the Health, Aging, and Body Composition study.
Journal of the American Geriatrics Society.
57(10):1767-75
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2009
Physical activity and maintaining physical function in older adults.
British journal of sports medicine.
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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
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Sarcopenia: Clinical Evaluation, Biological Markers and Other Evaluation Tools
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Sarcopenia: clinical evaluation, biological markers and other evaluation tools.
The journal of nutrition, health & aging.
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Self-assessed health status, walking speed and mortality in older Mexican-Americans.
Gerontology.
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Skeletal muscle and mortality results from the InCHIANTI Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
64(3):377-84
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2009
Stopping to rest during a 400-meter walk and incident mobility disability in older persons with functional limitations.
Journal of the American Geriatrics Society.
57(2):260-5
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2009
The Ace I/D Genotype and Improvement in 400-Meter Walk Performance With Exercise Training in the Lifestyle Intervention and Independence for Elders Pilot (Life-P)
Journal of the American Geriatrics Society.
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What is a meaningful change in physical performance? Findings from a clinical trial in older adults (the LIFE-P study).
The journal of nutrition, health & aging.
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2008
A Cost Analysis of a Physical Activity Intervention for Older Adults
Annals of Behavioral Medicine.
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Association Between Changes in Inflammation and Risk for Mobility Disability
Gerontologist.
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Chronic Inflammation Is Associated With Low Physical Function in Older Adults Across Multiple Comorbidities
Gerontologist.
48:491-492
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Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
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2008
Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial.
Journal of applied physiology (Bethesda, Md. : 1985).
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2008
Exercise training and plasma C-reactive protein and interleukin-6 in elderly people.
Journal of the American Geriatrics Society.
56(11):2045-52
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2008
Functional outcomes for clinical trials in frail older persons: time to be moving
Journals of Gerontology Series A-Biological Sciences and Medical Sciences.
63:160-164
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Interaction between angiotensin converting enzyme insertion/deletion genotype and exercise training on knee extensor strength in older individuals.
International journal of sports medicine.
29(1):40-4
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Maximal fitness testing in sedentary elderly at substantial risk of disability: LIFE-P study experience.
Journal of aging and physical activity.
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2008
Physical activity in prefrail older adults: confidence and satisfaction related to physical function.
The journals of gerontology. Series B, Psychological sciences and social sciences.
63(1):P19-26
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2008
Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study.
BMC geriatrics.
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2008
Physical function, physical activity and recent falls. Results from the “Invecchiamento e Longevita nel Sirente (ilSIRENTE)” Study
Aging Clinical and Experimental Research.
20:234-241
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Physical function, physical activity and recent falls. Results from the “Invecchiamento e Longevità nel Sirente (ilSIRENTE)” Study.
Aging clinical and experimental research.
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2008
Predictors of Risk for Major Mobility Disability in the Lifestyle Interventions and Independence for Elders Pilot (Life-P)
Gerontologist.
48:197-198
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Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly.
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2008
Stopping To Rest During a 400-Meter Walk and Incident Mobility Disability in Older Persons With Functional Limitations
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2008
The Burning Issue of Inflammaging
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The Magnitude and Meaning of Performance Change in a Clinical Trial: the Life-P Study
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Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study.
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Anticholinergic drugs and physical function among frail elderly population.
Clinical pharmacology and therapeutics.
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2007
Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study).
Journal of geriatric psychiatry and neurology.
20(3):131-7
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2007
Designing clinical trials of interventions for mobility disability: results from the lifestyle interventions and independence for elders pilot (LIFE-P) trial.
The journals of gerontology. Series A, Biological sciences and medical sciences.
62(11):1237-43
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2007
Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study.
Archives of internal medicine.
167(11):1137-44
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2007
Effects of birth cohort and age on body composition in a sample of community-based elderly.
The American journal of clinical nutrition.
85(2):405-10
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Free insulin-like growth factor-I and cognitive function in older persons living in community.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
17(1):58-66
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2007
HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study).
Age and ageing.
36(5):514-20
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2007
Health-related quality of life in older adults at risk for disability.
American journal of preventive medicine.
33(3):214-8
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2007
Impact of inappropriate drug use on physical performance among a frail elderly population living in the community
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36:514-520
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Impact of inappropriate drug use on physical performance among a frail elderly population living in the community.
European journal of clinical pharmacology.
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Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study.
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Lifestyle Interventions and Independence for Elders pilot study: recruitment and baseline characteristics.
Journal of the American Geriatrics Society.
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Physical activity and risk of cognitive impairment among older persons living in the community.
Aging clinical and experimental research.
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Polymorphisms of angiotensinogen and angiotensin-converting enzyme associated with lower extremity arterial disease in the Health, Aging and Body Composition study.
Journal of human hypertension.
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2007
Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
62(5):563-9
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2007
Research partnership with underserved African-American communities to improve the health of older persons with disability: a pilot qualitative study.
Aging clinical and experimental research.
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The clinically meaningful change in physical performance scores in an elderly cohort.
Aging clinical and experimental research.
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2007
Treatment of minor depression in older adults: A pilot study comparing sertraline and exercise
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Treatment of minor depression in older adults: a pilot study comparing sertraline and exercise.
Aging & mental health.
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Walking while talking: effect of task prioritization in the elderly.
Archives of physical medicine and rehabilitation.
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Abdominal obesity is an independent risk factor for chronic heart failure in older people.
Journal of the American Geriatrics Society.
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Anemia and cognitive performance in hospitalized older patients: results from the GIFA study.
International journal of geriatric psychiatry.
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Anemia and recovery from disability in activities of daily living in hospitalized older persons.
Journal of the American Geriatrics Society.
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Anemia in old age is associated with increased mortality and hospitalization.
The journals of gerontology. Series A, Biological sciences and medical sciences.
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Anemia, physical disability, and survival in older patients with heart failure.
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Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability.
JAMA.
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Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study).
Gerontology.
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Determinants of high and low attendance to diet and exercise interventions among overweight and obese older adults. Results from the arthritis, diet, and activity promotion trial.
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27(3):227-37
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Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
61(11):1157-65
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Effects of ACE inhibitors on skeletal muscle.
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2006
Effects of caloric restriction and exercise on age-related, chronic inflammation assessed by C-reactive protein and interleukin-6.
The journals of gerontology. Series A, Biological sciences and medical sciences.
61(3):211-7
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Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study.
The American journal of clinical nutrition.
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Impact of inflammation on the relationship among alcohol consumption, mortality, and cardiac events: the health, aging, and body composition study.
Archives of internal medicine.
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Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community
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63:438-442
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Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community.
Occupational and environmental medicine.
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Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle.
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Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders.
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Physical exercise and comorbidity. Results from the Fitness and Arthritis in Seniors Trial (FAST).
Aging clinical and experimental research.
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Physical Performance Measures as Predictors of Mortality in a Cohort of Community-dwelling Older French Women
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Physical performance measures as predictors of mortality in a cohort of community-dwelling older French women.
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Plasminogen activator inhibitor type 1 gene polymorphisms and haplotypes are associated with plasma plasminogen activator inhibitor type 1 levels but not with myocardial infarction or stroke
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152:1109-1115
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Plasminogen activator inhibitor type 1 gene polymorphisms and haplotypes are associated with plasma plasminogen activator inhibitor type 1 levels but not with myocardial infarction or stroke.
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Randomized controlled trials involving multidisciplinary interventions in the community.
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Study IotGIdFnA. Anemia, physical disability, and survival in older patients with heart failure
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The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers
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A cost-minimization analysis of diuretic-based antihypertensive therapy reducing cardiovascular events in older adults with isolated systolic hypertension
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A cost-minimization analysis of diuretic-based antihypertensive therapy reducing cardiovascular events in older adults with isolated systolic hypertension.
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Anemia is associated with depression in older adults: results from the InCHIANTI study.
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Angiotensin-converting enzyme inhibition intervention in elderly persons: effects on body composition and physical performance.
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Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline.
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Association of Visceral Adipose Tissue With Incident Myocardial Infarction in Older Men and Women: The Health, Aging and Body Composition Study
Obstetrical & Gynecological Survey.
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Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training
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Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training.
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Bone density and hemoglobin levels in older persons: results from the InCHIANTI study
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Bone density and hemoglobin levels in older persons: results from the InCHIANTI study.
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Does aspirin attenuate the beneficial effect of ACE inhibitors in elderly people with heart failure?
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Effects of exercise adherence on physical function among overweight older adults with knee osteoarthritis
Arthritis & Rheumatology.
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Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults.
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Evaluation of continuous summary physical performance scores (CSPPS) in an elderly cohort.
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Inflammatory markers and cardiovascular health in older adults.
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Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study.
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Long-term exercise therapy resolves ethnic differences in baseline health status in older adults with knee osteoarthritis.
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Measures of physical performance and risk for progressive and catastrophic disability: results from the Women’s Health and Aging Study.
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Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritis.
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Prognostic value of usual gait speed in well-functioning older people–results from the Health, Aging and Body Composition Study.
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Sarcopenia, obesity and inflammation â Results from theTrial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
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82:428-434
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Sarcopenia, obesity, and inflammation–results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study.
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The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy.
Aging clinical and experimental research.
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The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods.
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Anemia is associated with disability and decreased physical performance and muscle strength in the elderly.
Journal of the American Geriatrics Society.
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Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats.
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Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study.
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Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study.
The American journal of clinical nutrition.
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Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study.
American journal of epidemiology.
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Designing randomized controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report
Journal of the American Geriatrics Society.
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Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial.
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Dietary-induced weight loss, exercise and chronic inflammation in older, obese adults: A randomized controlled clinical trial
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Dietary-induced weight loss, exercise and chronic inflammation in older, obese adults: A randomized controlled clinical trial
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79:544-551
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Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet and Activity Promotion Trial (ADAPT)
Arthritis & Rheumatology.
50:1501-1510
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Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial.
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Hemoglobin levels and skeletal muscle: results from the InCHIANTI study.
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Inflammatory Markers and Physical Function Among Older Adults with Knee Osteoarthritis
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Inflammatory markers and physical function among older adults with knee osteoarthritis.
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Inflammatory markers and physical performance in older persons: the InCHIANTI study.
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Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the Health, Aging, and Body Composition study.
Circulation.
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2004
Reliability of the 400-m usual-pace walk test as an assessment of mobility limitation in older adults.
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2004
Use of angiotensin-converting enzyme inhibitors in elderly people with heart failure: prevalence and outcomes.
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Anemia and decline in physical performance among older persons.
The American journal of medicine.
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2003
Association between ACE inhibitors use and headache caused by nitrates among hypertensive patients: results from the Italian group of pharmacoepidemiology in the elderly (GIFA)
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Association between ACE inhibitors use and headache caused by nitrates among hypertensive patients: results from the Italian group of pharmacoepidemiology in the elderly (GIFA).
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2003
Beta-blockers after acute myocardial infarction in elderly patients with diabetes mellitus: time to reassess.
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Depression and adverse drug reactions among hospitalized older adults.
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Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.
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Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA).
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Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study).
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Inflammatory markers and cognition in well-functioning African-American and white elders
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Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study.
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Inflammatory markers and onset of cardiovascular events: results from the Health ABC study.
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One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women.
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The effects of cognitive impairment on mortality among hospitalized patients with heart failure.
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ACE inhibitors use and changes in muscle strength and physical performance in older women
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Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP).
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Body mass index, weight change, and death in older adults: the systolic hypertension in the elderly program.
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Change in physical performance over time in older women: the Women’s Health and Aging Study.
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Evaluation and correction for a ‘Training Effect’ in the cognitive assessment of older adults
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Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology.
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Fosinopril versus amlodipine comparative treatments study: a randomized trial to assess effects on plasminogen activator inhibitor-1.
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Obese, older adults with knee osteoarthritis: weight loss, exercise, and quality of life.
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Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study.
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Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study.
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Trends in prescribing ACE-inhibitors for congestive heart failure in elderly people.
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An animal model of physical disability: a preclinical strategy for improving assessment and intervention
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Aortic stiffness is associated with visceral adiposity in older adults enrolled in the study of health, aging, and body composition.
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Predicting length of stay of older patients with exacerbated chronic obstructive pulmonary disease
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Glycemic control of older adults with type 2 diabetes: findings from the Third National Health and Nutrition Examination Survey, 1988-1994.
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Evidence for a black-white cross-over in all-cause and coronary heart disease mortality from a prospective study of an older population: the North Carolina EPESE
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