Jana Opavska

Jana Opavska, MSc

Scientific Laboratory Manager

Department: MD-ANATOMY-GENERAL
Business Phone: (352) 294-8599
Business Email: jopavska@ufl.edu

Publications

Academic Articles
2024
Genome-wide methylation profiling of Peripheral T-cell lymphomas identifies TRIP13 as a critical driver of tumor proliferation and survival.
Research square. [DOI] 10.21203/rs.3.rs-3971059/v1. [PMID] 38464090.
2024
Genome-Wide Methylation Profiling of Peripheral T-Cell Lymphomas Identifies TRIP13 as a Critical Driver of Tumor Proliferation and Survival.
Epigenomes. 8(3) [DOI] 10.3390/epigenomes8030032. [PMID] 39189258.
2021
Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
The Journal of biological chemistry. 296 [DOI] 10.1016/j.jbc.2021.100285. [PMID] 33450231.
2021
Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.
EBioMedicine. 63 [DOI] 10.1016/j.ebiom.2020.103191. [PMID] 33418509.
2019
Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.
Nature communications. 10(1) [DOI] 10.1038/s41467-019-12355-7. [PMID] 31558711.
2016
Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma.
PLoS genetics. 12(9) [DOI] 10.1371/journal.pgen.1006334. [PMID] 27690235.
2016
Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice.
Scientific reports. 6 [DOI] 10.1038/srep34222. [PMID] 27677595.
2016
Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.
Cell reports. 15(6):1190-201 [DOI] 10.1016/j.celrep.2016.04.004. [PMID] 27134162.
2015
Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.
Oncogene. 34(43):5436-5446 [DOI] 10.1038/onc.2014.472. [PMID] 25639876.
2014
Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis.
Leukemia. 28(5):1138-42 [DOI] 10.1038/leu.2013.364. [PMID] 24292811.
2013
Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.
Molecular and cellular biology. 33(21):4321-33 [DOI] 10.1128/MCB.00776-13. [PMID] 24001767.
2012
Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.
The Journal of clinical investigation. 122(1):163-77 [DOI] 10.1172/JCI57292. [PMID] 22133874.
2008
Mouse development with a single E2F activator.
Nature. 454(7208):1137-41 [DOI] 10.1038/nature07066. [PMID] 18594513.
2007
Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
Proceedings of the National Academy of Sciences of the United States of America. 104(39):15400-5 [PMID] 17881568.
2003
Extra-embryonic function of Rb is essential for embryonic development and viability.
Nature. 421(6926):942-7 [PMID] 12607001.

Contact Details

Phones:
Business:
(352) 294-8599
Emails:
Business:
jopavska@ufl.edu
Addresses:
Business Mailing:
PO Box 103633
GAINESVILLE FL 32610
Business Street:
CGRC 265
2033 Mowry RD
Gainesville FL 32610