David Julian

David Julian,

ASO PROFESSOR

Department: LS-BIOLOGY
Business Phone: (352) 392-5878
Business Email: djulian@ufl.edu

Teaching Profile

Courses Taught
2008,2012-2017,2017-2024
ZOO4926 Special Topics in Zoology
2019-2024
BSC4930 Special Topics in Biology
2014-2018,2020-2024
PCB3713C Cellular and Systems Physiology
2020,2022-2024
BOT4935 Special Topics
2018-2022
IDS4930 Special Topics in Interdisciplinary Studies
2021
ZOO4911 Undergraduate Research in Zoology
2018-2020
BOT6935 Special Topics
2008,2013-2017,2017-2020,2020
ZOO6927 Special Topics in Zoology
2016,2018
ISC3523 Integrative Biomedical Science
2016
IDH3931 Interdisciplinary Junior Honors
2006-2007,2009-2012,2011-2014
PCB4723C Physiology and Molecular Biology of Animals
2012-2013
PCB3713 Cellular and Systems Physiology
2012
IDH2931 Honors Seminar
2010
BSC2011 Integrated Principles of Biology 2
2009-2010
BSC2044L Accelerated, Integrated Principles of Biology Laboratory
2006-2007,2009-2010
BSC2010 Integrated Principles of Biology 1
2010
ZOO3603C Evolu Developme Biol
2009-2010
IDH4905 Individual Work
2009
IDH4917 Undergrad Research
2009
BSC2008 Evolu Ecol and Behavior

Research Profile

Basic Research. My basic science research area is comparative physiology, with a specific focus on cellular responses and adaptations of animals to environmental stressors. The overall goal of my research is to help elucidate the cellular, biochemical, and molecular adaptations that allow animals to avoid cellular damage when faced with extremes of oxidative stress, hydrogen sulfide, oxygen, salinity, pH and temperature. To investigate the impact of multiple stressors in cells and small organisms (such as C. elegans and larvae of marine invertebrates), my laboratory has developed high-content screening techniques to assess cellular and molecular responses to combinations of stressors or pharmaceutical compounds.

Mentoring and Education. My outreach and service efforts are devoted to STEM education transformation and minority biomedical workforce development. I direct two programs at UF that are designed to increase number of undergraduates from groups traditionally under-represented (UR) in the sciences who successful pursue research careers: the MARC Gator-STAR program, and the SF2UF Bridge to Baccalaureate Program (a partnership with the two-year Santa Fe College); the BioScience Scholars Program (a combined BS/MS program for low-income students). I also established and directed the X-Laboratory Program (a cross-disciplinary undergraduate laboratory for freshmen that merges biology, chemistry, physics, and mathematics while teaching basic research skills). Additional education-related research activity includes the development of online learning tools for teaching human physiology to undergraduates and medical students.

Open Researcher and Contributor ID (ORCID)

0000-0003-1143-2813

Publications

2016
Inhibition of the oxidative stress response by heat stress in Caenorhabditis elegans.
The Journal of experimental biology. 219(Pt 14):2201-11 [DOI] 10.1242/jeb.135327. [PMID] 27207646.
2015
Multiple-stressor interactions influence embryo development rate in the American horseshoe crab, Limulus polyphemus.
The Journal of experimental biology. 218(Pt 15):2355-64 [DOI] 10.1242/jeb.117184. [PMID] 26026044.
2011
Hydrogen sulfide increases nitric oxide production from endothelial cells by an akt-dependent mechanism.
Frontiers in physiology. 2 [DOI] 10.3389/fphys.2011.00104. [PMID] 22194727.
2010
Hydrogen sulfide induces oxidative damage to RNA and DNA in a sulfide-tolerant marine invertebrate.
Physiological and biochemical zoology : PBZ. 83(2):356-65 [DOI] 10.1086/597529. [PMID] 19327040.
2010
The hydrogen sulfide signaling system: changes during aging and the benefits of caloric restriction.
Age (Dordrecht, Netherlands). 32(4):467-81 [DOI] 10.1007/s11357-010-9150-z. [PMID] 20502969.
2009
Assessment of cellular and functional biomarkers in bivalves exposed to ecologically relevant abiotic stressors.
Journal of aquatic animal health. 21(2):104-16 [DOI] 10.1577/H08-066.1. [PMID] 19873832.
2008
Hypotaurine and sulfhydryl-containing antioxidants reduce H2S toxicity in erythrocytes from a marine invertebrate.
The Journal of experimental biology. 211(Pt 24):3816-25 [DOI] 10.1242/jeb.021303. [PMID] 19043054.
2008
Oxygen and steroid concentrations in preovulatory follicles of lactating dairy cows exposed to acute heat stress.
Theriogenology. 69(7):805-13 [DOI] 10.1016/j.theriogenology.2007.12.008. [PMID] 18243293.
2007
Autophagy in the heart and liver during normal aging and calorie restriction.
Rejuvenation research. 10(3):281-92 [PMID] 17665967.
2006
Increased expression of stress proteins in the surf clam Donax variabilis following hydrogen sulfide exposure.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 145(2):245-57 [PMID] 16890466.
2005
Mitochondrial depolarization following hydrogen sulfide exposure in erythrocytes from a sulfide-tolerant marine invertebrate.
The Journal of experimental biology. 208(Pt 21):4109-22 [PMID] 16244170.
2005
Sodium nitroprusside potentiates hydrogen-sulfide-induced contractions in body wall muscle from a marine worm.
The Biological bulletin. 209(1):6-10 [PMID] 16110089.
2004
Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats.
FEBS letters. 577(3):483-90 [PMID] 15556633.
2004
Linkage between insulin and the free radical theory of aging.
American journal of physiology. Regulatory, integrative and comparative physiology. 286(1):R20-1 [PMID] 14660473.
2003
Oxygen consumption in weakly electric Neotropical fishes.
Oecologia. 137(4):502-11 [PMID] 14505027.
2002
Enzymatic hydrogen sulfide production in marine invertebrate tissues.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 133(1):105-15 [PMID] 12160876.

Grants

May 2024 ACTIVE
GATORAADE: Gators Advancing Through Opportunities in Research for Aging and Alzheimer's Disease Education
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Jun 2022 ACTIVE
MARC at the University of Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Aug 2021 ACTIVE
SF2UF: The Bridges to the Baccalaureate partnership between Santa Fe College and the University of Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jun 2016 – May 2023
GATORSTAR: A NEW MARC U*STAR PROGRAM AT THE UNIVERSITY OFFLORIDA
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Aug 2015 – May 2022
SF2UF: A New Bridges Baccalaureate program between Santa Fe College and the University of Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Aug 2015 – Apr 2018
Development of a Simulation-Based Application for Teaching Human Physiology through Guided Discovery, Pure Discovery, and Authentic Research
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Aug 2013 – Jul 2020
The Biosciences Scholars Program: Bringing the Master's Degree within REACH
Role: Principal Investigator
Funding: NATL SCIENCE FOU

Education

Post-doc, Biochemistry
2000 · Institut für Zoophysiologie, Universität Düsseldorf, Germany
Post-doc, Marine Biology
1999 · Estuary & Ocean Science Center, Tiburon, CA
PhD, Physiology
1997 · University of California, San Francisco
MA, Physiology and Behavioral Biology
1991 · San Francisco State University
BS, Biology
1988 · San Francisco State University

Contact Details

Phones:
Business:
(352) 392-5878
Emails:
Business:
djulian@ufl.edu
Addresses:
Business Mailing:
PO Box 118525
GAINESVILLE FL 32611
Business Street:
123 BAR
GAINESVILLE FL 32611