Shuang Huang, PhD
Professor
On This Page
Teaching Profile
Courses Taught
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GMS6647 – Transcriptional and Translational Control of Cell Growth and Proliferation
College of Medicine
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GMS6691 – Special Topics in Cell Biology and Anatomy
College of Medicine
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GMS6064 – Tumor Biology
College of Medicine
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GMS6421 – Cell Biology
College of Medicine
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GMS7979 – Advanced Research
College of Medicine
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GMS7980 – Research for Doctoral Dissertation
College of Medicine
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GMS6644 – Apoptosis
College of Medicine
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GMS5905 – Special Topics in Biomedical Sciences
College of Medicine
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GMS6471 – Core Principles of Physiology
College of Medicine
Research Profile
Research in the Huang lab is concentrated on elucidating molecular mechanisms associated with breast and ovarian cancer metastasis. One of the current projects is to investigate how homeobox domain-containing proteins SHOX2 and HOXC8 regulate breast cancer metastasis with the focus on their role in epithelial-mesenchymal transition (EMT). Another project is based on our early discovery that the integrity of EPS8/ABI1/SOS1 tri-complex is critical for ovarian cancer metastasis. In this project, we are currently dissecting the players and pathways pertinent to the metastasis-promoting role of EPS8/ABI1/SOS1 tri-complex in ovarian cancer. In addition, the Huang lab is also working on identifying cancer driver genes/pathways in ovarian cancer, with the emphasis on developing targeted therapeutic strategies against ovary malignancies.
RESEARCH PROJECTS
Role of SHOX2 in breast tumor progression and metastasis R01, National Cancer Institute (CA187152) August 1, 2014 to July 31, 2019
Potential of Targeting PDE1C/2A for Suppressing Metastatic Ovarian Cancers Pilot Award, Department of Defense Ovarian Cancer Research Program July 1, 2013 to June 30, 2015
Publications
Academic Articles
Grants
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Improving immunotherapy effectiveness in ovarian cancer by mitigating immunosuppressive tumor microenvironment
Active
- Role:
- Principal Investigator
- Funding:
- OCALA ROYAL DAMES FOR CANCER RESEARCH
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Novel protein kinase signaling associated with platinum resistance in ovarian cancer
Active
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NCI
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Early Detection of Breast Cancer in the Urine using CRISPR
- Role:
- Co-Investigator
- Funding:
- FL BREAST CANCER FOU
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Impact of microRNA processing on EMT of ovarian cancer cells
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NCI
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Role of SHOX2 in breast tumor progression and metastasis
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NCI
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Deterring breast cancer metastasis by restoring miRNA processing
- Role:
- Principal Investigator
- Funding:
- FL BREAST CANCER FOU
Education
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Post Doctoral Fellowship
American Cancer Society
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PhD, Pharmacology
Baylor College of Medicine, Houston, Texas
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BSc, Neurobiology
Fundan University, Shanghai, China
Contact Details
- Business:
- (352) 273-6769
- Business:
- shuanghuang@ufl.edu
- Business Mailing:
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PO Box 103633
GAINESVILLE FL 32610 - Business Street:
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CGRC 355
2033 MOWRY RD
Gainesville FL 32610