Hannah Costello,
Dr.
Department:
Department of Physiology and Aging
Business Phone:
7500 781182
Business Email:
hannahcostello@ufl.edu
Publications
Academic Articles
2024
Sex differences in the adrenal circadian clock: A role for BMAL1 in the regulation of urinary aldosterone excretion and renal electrolyte balance in mice.
American journal of physiology. Renal physiology.
[DOI] 10.1152/ajprenal.00177.2024.
[PMID] 39447118.
2023
Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.
Function (Oxford, England).
4(2)
[DOI] 10.1093/function/zqad001.
[PMID] 36778748.
2023
Circadian Disruption and the Molecular Clock in Atherosclerosis and Hypertension.
The Canadian journal of cardiology.
39(12):1757-1771
[DOI] 10.1016/j.cjca.2023.06.416.
[PMID] 37355229.
2023
Defining the age-dependent and tissue-specific circadian transcriptome in male mice.
Cell reports.
42(1)
[DOI] 10.1016/j.celrep.2022.111982.
[PMID] 36640301.
2023
High salt intake activates the hypothalamic-pituitary-adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice.
Cardiovascular research.
119(8):1740-1750
[DOI] 10.1093/cvr/cvac160.
[PMID] 36368681.
2023
Male kidney-specific BMAL1 knockout mice are protected from K+-deficient, high-salt diet-induced blood pressure increases.
American journal of physiology. Renal physiology.
325(5):F656-F668
[DOI] 10.1152/ajprenal.00126.2023.
[PMID] 37706232.
2023
Mapping the Transcriptome Underpinning Acute Corticosteroid Action within the Cortical Collecting Duct.
Kidney360.
4(2):226-240
[DOI] 10.34067/KID.0003582022.
[PMID] 36821614.
2023
Sodium-glucose cotransporter 2 inhibition does not improve the acute pressure natriuresis response in rats with type 1 diabetes.
Experimental physiology.
108(3):480-490
[DOI] 10.1113/EP090849.
[PMID] 36644793.
2023
The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats.
Canadian journal of physiology and pharmacology.
101(3):136-146
[DOI] 10.1139/cjpp-2022-0134.
[PMID] 36450128.
2022
Circadian clocks of the kidney: function, mechanism, and regulation.
Physiological reviews.
102(4):1669-1701
[DOI] 10.1152/physrev.00045.2021.
[PMID] 35575250.
2022
Kidney-specific KO of the circadian clock protein PER1 alters renal Na+ handling, aldosterone levels, and kidney/adrenal gene expression.
American journal of physiology. Renal physiology.
322(4):F449-F459
[DOI] 10.1152/ajprenal.00385.2021.
[PMID] 35129370.
2022
Knockout of the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension and Increases Kidney Injury in Dahl Salt-Sensitive Rats.
Hypertension (Dallas, Tex. : 1979).
79(11):2519-2529
[DOI] 10.1161/HYPERTENSIONAHA.122.19316.
[PMID] 36093781.
2021
Activation of the Sympathetic Nervous System Promotes Blood Pressure Salt-Sensitivity in C57BL6/J Mice.
Hypertension (Dallas, Tex. : 1979).
77(1):158-168
[DOI] 10.1161/HYPERTENSIONAHA.120.16186.
[PMID] 33190558.
2021
Circadian Rhythm Effects on the Molecular Regulation of Physiological Systems.
Comprehensive Physiology.
12(1):2769-2798
[DOI] 10.1002/cphy.c210011.
[PMID] 34964116.
2021
Circadian Rhythm, Clock Genes, and Hypertension: Recent Advances in Hypertension.
Hypertension (Dallas, Tex. : 1979).
78(5):1185-1196
[DOI] 10.1161/HYPERTENSIONAHA.121.14519.
[PMID] 34601963.
2019
A novel role for myeloid endothelin-B receptors in hypertension.
European heart journal.
40(9):768-784
[DOI] 10.1093/eurheartj/ehy881.
[PMID] 30657897.
2019
Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation.
American journal of physiology. Renal physiology.
317(6):F1536-F1548
[DOI] 10.1152/ajprenal.00372.2019.
[PMID] 31588796.
2019
Impaired pressure natriuresis and non-dipping blood pressure in rats with early type 1 diabetes mellitus.
The Journal of physiology.
597(3):767-780
[DOI] 10.1113/JP277332.
[PMID] 30537108.
Grants
Jan 2022
– Dec 2023
Contribution of the adrenal clock to renal function
Role: Principal Investigator
Funding: AMER HEART ASSOCIATION
Education
Ph.D.
2017-2020
·
University of Edinburgh
MSc
2016-2017
·
University of Edinburgh
BSc with Honours
2012-2016
·
University of Dundee
Contact Details
Phones:
- Business:
- 7500 781182
Emails:
- Business:
- hannahcostello@ufl.edu
Addresses:
- Business Mailing:
-
8 BAILIELANDS
LINLITHGOW FL EH497SU - Business Street:
-
Department of Physiology & Aging
1345 Center Drive
Gainesville FL 32610